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When a patient asks me should I take Mounjaro or Zepbound? the answer often comes down to which one their insurance covers not pharmacology

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13 Overall, the benefit-risk profile of anti-obesity injections, particularly GLP-1 receptor agonists, remains favorable for many patients with obesity

Mechanisms of Action and Therapeutic Application of GLP-1 and GIP. Cell Metabolism

However, OCTN1 and OCTN2 both have narrower substrate specificity compared to polyspecific OCTs and OATs, and uptake assays performed with a large panel of drugs suggest that OCTN2 is not a general drug transporter 3,12,17,18