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In our experiments, exogenous rapamycin significantly decreased the proportion of SA--Gal-positive cells and p16 expression, whereas autophagy inhibitors 3-MA and Baf-A1 produced opposite effects

There were significant changes in the liver transcriptome in response to semaglutide, as shown by separated clustering of the two groups of samples (Figure 4A)

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8 In 2000, the hallmarks of cancer were articulated, and by 2013, a similar framework was established for aging, identifying twelve hallmarks that collectively define the aging process across species

An individualised, shared decision-making approach is re commended