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Neonatal mouse intestinal cell culture Newborn mice (C57BL/6) from Charles River Laboratories (Wilmington, MA) were used for preparation of mixed primary intestinal cell cultures enriched with L-cells using a modification of previously published techniques 36,37,38
At week 64, participants taking the once-daily 25mg dose along with a reduced calorie diet and exercise achieved an average weight loss of 13.6 percent compared with 2.4 percent for placebo, with a greater effect (16.6 percent) in those fully compliant with therapy versus 2.7 percent with placebo
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