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Animals A total of 90 adult male Wistar rats, weighing approximately 200 to 250 g, were purchased from the Animal Experiment Center of the Chinese Academy of Medical Sciences, Beijing, China and were maintained in wooden cages at a temperature of 27 C30 C, with a 12 h light-dark photo-periodicity cycle

Treatment of Pla2g6 / mice with semaglutide significantly increased CREB mRNA levels compared to untreated Pla2g6 / mice and restored expression levels to those observed in the wild-type controls

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