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Some research suggests berberine may support the release of GLP-1 by stimulating bitter receptors in the gut
Possible side effects of GLP-1 patches include: Skin irritation or rash Increased heart rate Jitteriness or anxiety Trouble sleeping Nausea Some ingredients act as stimulants and may raise blood pressure or interact with other medications
The medication is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist that works by enhancing glucose-dependent insulin secretion, suppressing glucagon release, and slowing gastric emptying
GLP-1Rs are widely expressed in areas of the mesolimbic reward pathway (eg, VTA) that receive direct projections from the NTS [49]
Tchang BG, Aras M, Kumar RB, et al
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