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Although the weight loss is considered clinically significant according to the clinical expert consulted by CADTH on this review, there is no clear evidence that this weight loss reduces the number of patients who may develop various weight-related comorbidities, including type 2 diabetes, cardiovascular disease, and osteoarthritis

Although 45% of dNETs stained positively for GLP-1R, the mean intensity score (H-score) was modest at 57

Data availability statement All data generated or analyzed during this study are included in this published article (and its supplementary information files)

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