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Our results, for the first time, point to a potential physiological trigger of gametocytogenesis in malaria

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Useful safety observations often include: Local tolerance: redness, irritation, swelling, or tenderness at the administration site Acute post-dose observations: changes in behavior, appetite, activity, or visible discomfort during the expected response window Pattern effects over time: whether repeated dosing appears to change tolerability or response consistency Protocol drift: missed timing windows, inconsistent preparation, or undocumented deviations that can confuse safety interpretation How dosing logic affects safety interpretation The why behind dosage matters most

Fact: While some mild shifts in digestion can occur during a transition, persistent diarrhea is generally a sign of malabsorption or gut irritation

4 = loss of crypts in large areas