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For example, stimulation of viral replication by inflammatory cytokines is optimal at decreased glutathione concentrations

However, like all medications, they may be associated with certain side effects, such as gastrointestinal issues, including nausea, vomiting, diarrhea, and constipation

*Cytokine regulation: GSH modulates the production of pro-inflammatory cytokines including IL-1, IL-6, TNF-, and IFN- - all of which are elevated in Hashimoto's thyroiditis and Graves' disease B-cell antibody production: Oxidative stress promotes B-cell activation and autoantibody production

However, pain that becomes more severe, spreads into the shoulder, limits arm movement, or continues for weeks may indicate something beyond routine post-vaccination discomfort