I wish you well I respect your judgement over mine, but I haven't found any deterioration in ampoules that have been stored in the dark but are a year beyond their date
This is the same principle behind why recombinant protein biologics (monoclonal antibodies, insulin analogues) are never shaken: air-water interfacial agitation unfolds polypeptide chains that then reassemble into non-native oligomers or fibrils
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Since the mid-2010s, multiple studies have explored its effects on musculoskeletal structures, including skeletal muscle, connective tissue, and bone, highlighting its relevance in regenerative research models
Common manifestations include: Musculoskeletal symptoms : Bone pain, muscle weakness, and increased susceptibility to fractures