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Monitor and Observe Patients may re-sedate if a long-acting opioid was used Observe for at least 4-6 hours after reversal for short-acting opioids

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After the intervention period, blood samples were obtained for the measurement of serum asymmetric dimethylarginine (ADMA), malondialdehyde (MDA), copper zinc-superoxide dismutase (CuZn-SOD), glutathione peroxidase (GSH-Px), high sensitivity C reactive protein (hsCRP) and pentraxin 3 (PTX3) concentration

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