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The study was conducted on mice that had not yet experienced conception, and prior stress induction was carried out so that they could be continued for human trials at the preconception stage and subjects who experienced mild stress
For gut patients, the timeline is even faster
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Overall, luteolin displays suboptimal pharmacokinetic performance characterized by limited aqueous solubility, low oral exposure, and rapid systemic clearance (Wang et al., 2024)
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