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Therapies, including finerenone, incretin-based therapy, SGLT-2 inhibitors, and emerging neuroprotective treatments may met the need for reducing NPDR progression

Moreover, the weak parasitic load encountered in chubs could result in limited efflux compared with pollutant uptake (but see Possible Confounding Factors Parasitism induces a cascade of physiological and ecological changes (metabolism, foraging ecology, and social interaction), which may in turn influence pollutants exposure and accumulation (Molbert et al., 2020)

PMID 28100881

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Parenteral administration (subcutaneous or intravenous) provides direct systemic availability