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For prevention or milder cases, it may also be available in oral tablet or sublingual (under the tongue) forms

doi:10.1073/pnas.1301816110 Mazza A, Cicero AF, Ramazzina E, et al

Effect of adjunctive Lmethylfolate 15 mg among inadequate responders to SSRIs in depressed patients who were stratified by biomarker levels and genotype: results from a randomized clinical trial

This mechanism might also operate to mount a FA-dependent response

Therefore, critically analyzing negative clinical results is necessary to avoid misleading conclusions, standardize the clinical relevance of endpoint indicators, and promote the rational development of the antiaging field