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In white adipose tissue, blocking NNMT elevated resting calorie burn, decreased adiposity, and improved insulin sensitivity in rodent models, independent of diet or activity changes (Kraus et al., Nature Medicine )

(2026), in the American Journal of Sports Medicine, stated this directly: indications, dosing, frequency, and duration of treatment remain unknown

They are not approved for human therapeutic use in Australia, and researchers are responsible for compliance with Therapeutic Goods Administration (TGA) regulations and their institution's protocols

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If the needle is going just under the skin (subcutaneous), hold it at a 45-degree angle