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Within- and between-group changes for anthropometric and some dietary variables, as well as physical activity, are provided in Table 2

While the results of this animal study cannot be extrapolated to humans with certainty, the extrapolation is supported by the understanding of the pathophysiologic mechanisms of the toxicity of cyanide and the mechanisms of the protective effect of hydroxocobalamin as examined in dogs

A 12-week Phase IIa trial involving 300 participants showed modest reductions in weight (2.6 kg versus 0.8 kg for placebo)

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10.1097/01.brs.0000263369.95182.19