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Always discuss supplements with your healthcare provider

Roles of continuous neurogenesis in the structural and functional integrity of the adult forebrain

Side effects could occur -- people were more likely to experience "mild to moderate gastrointestinal events" while on tirzepatide long-term versus placebo, the team noted

They do not address vaginal atrophy, hot flashes, or bone density on the timeline HRT does

Differences in trial design, participant populations, treatment duration, and endpoints mean that direct numerical comparisons between retatrutide Phase 2 data and semaglutide Phase 3 data are hypothesis-generating, not definitive