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Pre-publication history The pre-publication history for this paper can be accessed here: Acknowledgements This study was funded by intramural funds from the New Jersey Neuroscience Institute and the Neurogenetics Foundation

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In summary, our extensive screening of 5170 drugs using HTS techniques led to the discovery of six new drugs, among which aminoacridine, abemaciclib, and the combination of aminoacridine with MXD showed promising results in animal models