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Lab measurements include total and free carnitine, fasting triglycerides, and beta-hydroxybutyrate (BHB)

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Appropriate application of MI and a suitable proportion of DCI improves the health of organs and tissues, while long-term high-dose DCI monotherapy in women with PCOS has a negative impact [184]

Consistent with our previous work (22), Dpp4 hep/ mice had significantly reduced Dpp4 mRNA expression in whole liver extracts (Supplemental Figure 2A)

Kynurenine is subsequently converted to NAD + in a chain of reactions with the rate-limiting step by quinolinic phosphoribosyltransferase (QPRT), which converts quinolinic acid into nicotinic acid mononucleotide (NAMN) 26 , finally entering the PreissHandler pathway