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Discovery of ecnoglutide - A novel, long-acting, cAMP-biased glucagon-like peptide-1 (GLP-1) analog

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Standard reconstitution with bacteriostatic water alone often fails for these sequences because neutral water leaves the peptide near the pH where it aggregates

Cagrilintide AUC 0168h ranged from 92624,271 nmol h/L, C max ranged from 6.14 to 170 nmol/L, t 1/2 ranged between 159195 h and median t max was 2472 h

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