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For example, type 2 diabetes increases FA uptake and oxidation in the heart ( FABP3 , which mediates FA transmembrane trafficking, was downregulated, while CPT1 , which mediates mitochondrial transport and -oxidation, was upregulated

[DOI] [PubMed] [Google Scholar] 37.Kraemer WJ, Volek JS, French DN, Rubin MR, Sharman MJ, Gomez AL, Ratamess NA, Newton RU, Jemiolo B, Craig BW, et al

tumor growth, metabolic effects) against benefits before initiating therapy in each patient

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They described treatment selection as individualized according to comorbidity burden, tolerability, and weight-loss goals