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Dev Comp Immunol (2017) 66:1209

Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage

Improving metabolic flexibility Mitochondria not only represent a site for fat -oxidation but are also a reaction site for metabolic processes such as protein synthesis/breakdown (14)

With second generation GLP-1 agonists (liraglutide, dulaglutide), emphasis turned to increasing protein binding, reducing renal clearance, thus further prolonging drug half-life to now permit weekly injectable formulations (e.g semaglutide)

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