Which is not to say he supports the change
A recent report from the Institute for Clinical and Economic Review, an independent nonprofit that evaluates the value of medical treatments, found that GLP-1s such as Ozempic, Wegovy and Zepbound are cost-effective, meaning the medications health benefits justify their price
Importantly, tricyclic antidepressants, especially amitriptyline and nortriptyline, worsen the metabolic profile, increasing insulin resistance, contributing to weight gain and causing hyperglycemia, thereby increasing the risk of diabetes with prolonged use [77]
The appetite-suppressing effects of the medication wear off as it leaves your system, and you may notice an increase in hunger within days or weeks of your last injection
Oncol Lett 7:13451351