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Their body is sending a "drink" signal because it does not have a separate signal for "you need salt." The body can only say "thirsty." It cannot say "your sodium is low, please eat something salty and then drink water." Sodium: the primary electrolyte concern Tirzepatide-induced natriuresis primarily affects sodium

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mTOR signaling, a downstream target of the insulin/IGF-1 pathway, is a well-known enhancer of the anabolic processes required during the growth phase when its capacity to inhibit autophagy might be beneficial but later in the lifespan, its inhibition promotes the degeneration of aging tissues

Nutrients 10 , 1154 (2018)