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10.3389/fneur.2020.00840 Front

Damage to the tight endothelial junctions results in increased BBB permeability, leading to the entry of immune cells and inflammatory cytokines into the parenchyma, as well as impaired clearance of metabolic waste and neurotoxic compounds (Zlokovic, 2004

Understanding Glutathione Glutathione, a powerful antioxidant, shields cells from oxidative stress and aids in removing toxins and harmful substances from the body

Still, it matters

A significant down-regulation of several other enzymes related to energy metabolism was also confirmed at the protein level in riboflavin deficient cells, such as DLD, SDHA, NDUFS1, and NDUFV2