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The TRANSCEND-T2D-1 trial reported in March 2026 found 16.8% weight loss and a 2.0% reduction in HbA1c (a marker of average blood sugar) at the 12 mg dose over 40 weeks in adults living with type 2 diabetes

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Demand outstripped supply

A conservative general window is about 28 days at 2-8 C when mixed with bacteriostatic water and handled cleanly