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163 GherardiRKCrpeauxGAuthierF-J

Riboflavin responsiveness may be related to its essential function as a precursor of FAD cofactor for ACAD enzyme activity and stability

doi:10.3390/ijms20163905 Ren Q, Zhi L, Liu H

published in Frontiers in Physiology confirmed that BPC-157 dose- and time-dependently increased GHR expression in isolated rat Achilles tendon fibroblasts at both mRNA and protein level, and that GH added to BPC-157-treated fibroblasts produced significant, dose-dependent increases in cell proliferation establishing GHR upregulation as a specific molecular mechanism through which BPC-157 enhances local tissue sensitivity to growth hormone signalling

Oliveri M, Koch G, Torriero S, Caltagirone C