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If you take levodopa/carbidopa (Sinemet) for Parkinson disease, take blood thinners like warfarin, use retinoid skin creams, or have diabetes or thyroid disease, talk with your pharmacist before using it several ingredients carry meaningful interactions

At a normal therapeutic dose, acetaminophen is primarily metabolized by the liver to sulfate and glucuronide conjugates, while a SMALL amount is metabolized by CYP2E1 to a highly reactive intermediate, N-acetyl-p-benzoquinone imine (NAPQI)

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