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Comparing the prognosis of ischemic stroke patients between survivors and non survivors, the IL-10 level in the survivors group was significantly higher than that in the non survivors group (P=0.006) (106)

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We hypothesized that disrupting this tether or lengthening the linker that connects the two -CTs may uncouple the two binding sites in the active state of IGF1R, reduce the negative cooperativity, and allow the binding of the second IGF1