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Glutathione peroxidase catalysis occurs in the presence of reduced glutathione, a tripeptide, in a paired reaction involving glutathione reductase, which regenerates reduced glutathione from oxidized glutathione (Handy and Loscalzo 2022)

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For others, with milder or temporary deficiencies, the initial shots might lead to longer periods of feeling well, potentially even allowing for a switch to oral supplements under strict medical guidance