Having said that, other people may gain weight quickly because of change in diet, or they develop a disability and their physical activity goes down, or they're on a weight-gaining drug for diabetes or something they can have rapid risk as well
Others claim they no longer need exercise
In the published Mounjaro trials, roughly 25-30% of total weight loss is from lean mass, including muscle
However, a lack of GLP-1R is also observed to trigger a stress response that boosts fibroblast growth factor 21 and elicits beneficial systemic effects such as memory improvement and glucose homeostasis (Timper et al., 2020)
Li CJ, Yu Q, Yu P, Yu TL, Zhang QM, Lu S, et al