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Severe Hypoglycemia Coadministration of SYMLIN with mealtime insulin increases the risk of severe hypoglycemia, particularly in patients with type 1 diabetes [see Boxed Warning and Warnings and Precautions (5.1)]

doi:10.1530/eje.0.1510483

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797 Even neonatal rat ventricular muscle cells with low sensitivity to GPX4 inhibition underwent ferroptosis in the presence of cysteine deprivation, suggesting that inhibition of GPX4 promotes ferroptosis of cardiomyocytes under metabolic stress, such as cysteine deprivation