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Polyalanine (PA), poly(alanine-co-phenylalanine), and poly(alanine-co-leucine) conjugated to PEG or poloxamer are some examples of thermosensitive copolymers

Key Features: Mimics ghrelin to increase GH pulse amplitude Does not significantly raise ACTH, prolactin, or cortisol Very low risk of water retention, appetite spikes, or gynecomastia Well-tolerated in both men and women As a standalone peptide, Ipamorelin can modestly boost GH output

Kennedy asserted that FDA can only make such a classification if there are safety concerns associated with the drug and claimed that these peptides do not pose any safety risks

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