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Appropriate trained and qualified staff may need to be deployed to these locations when time permits, and the capacity of general healthcare staff capacity to provide mental health and psychosocial support should be increased (see the mhGAP Humanitarian Intervention Guide)
Bock-Bierbaum, T
Given that dyslipidemia is a key component of metabolic syndrome, and cardiovascular outcomes are of the utmost importance in managing such patients, a combination approach may yield better results than GLP-1RA monotherapy in this aspect 30
In addition to the widely established IR-Tac, granulate formulation extended release (ER)-Tac (Advagraf) with a prolonged drug release (90% absorption after 612 h) and LCP-Tac (Envarsus) with an additional improved bioavailability have been established in clinical practice, reviewed in detail by Piotti et al
