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Analyzing molecular recognition of retatrutide by GLP-1R, GIPR and GCGR highlights that the triple agonism is achieved through a combination of maintaining common interactions with conserved residues and accommodating receptor-specific residues with variable contacts primarily in the upper half of the TMD pocket (Fig

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Loh JS, Mak WQ, Tan LKS, et al

When approached for comment, the MHRA said it was in the process of finalising the review

acceleration of glucose transport in the body