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[DOI] [PMC free article] [PubMed] [Google Scholar] 40.Crockett A, Hollis F

Firstly, it enhances insulin secretion from pancreatic beta cells in a glucose-dependent manner, meaning insulin is released only when blood glucose levels are elevated, thereby reducing the risk of hypoglycaemia

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In the SURMOUNT clinical trial series, participants maintained weight loss for up to 2 years when continuing the medication, losing an average of 2022% of body weight at higher doses

Key findings from this study include (see Figure 2): Prevalence of OLLMM by age increases from 5.1% for age group 20-29, to 12.5% for age group 50-59, 20.2% for age group 60-69, 36.8% for age group 70-79, and 38.7% for age group 80