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Meanwhile, ACSL4 is regulated by multiple factors, such as integrin 64-mediated inhibition of ACSL 4 expression by Src and signal transducer and activator of transcription 3 (STAT3) or activation of the androgen receptor (55)

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The overall mortality rate is less than 5%, mostly from complications such as skin superinfection, multiorgan dysfunction, and disseminated intravascular coagulation

In these cases one must infer that the G6PD() state is a selective disadvantage for hematopoietic stem cells