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References PubMed The antioxidant glutathione: protective roles, cofactor functions, and regeneration mechanisms PubMed Glutathione and glutathione-dependent enzymes: coordinated defense against oxidative stress PMC Glutathione: roles in immune function, detoxification, and clinical applications PubMed The interplay of glutathione-related processes in antioxidant defense PMC Exploring safety and efficacy of glutathione supplementation: narrative review PubMed Glutathione as a skin-lightening agent and in melasma: systematic review PMC Glutathione: pharmacological aspects and implications for clinical use in NAFLD PubMed Oxidative stress: role of mitochondria and protection by glutathione PMC Efficacy of glutathione for NAFLD treatment: open-label pilot study PMC Protective effect of glutathione against oxidative stress-induced cytotoxicity via Nrf2/HO-1 pathway PubMed Glutathione in the treatment of liver diseases: clinical practice insights Nature Glutathione system enhancement for cardiac protection against oxidative stress PubMed Clinical effect of glutathione on skin color and related conditions: systematic review PMC Glutathione and its antiaging and antimelanogenic effects: RCT at 250 mg/day PubMed Oxidative stress and regulation of glutathione in lung inflammation PMC Subcutaneous drug injection review: pharmacologic considerations CDC Vaccine administration: subcutaneous route (angle/site

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Their mechanism of action is independent from insulin secretion or action and is not affected by pancreatic -cell function, making them a suitable potential therapy at any stage of T2DM progression [95]

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