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Chong NW, Bernard M, Klein DC

Providers who prescribe without lab monitoring are missing critical safety data

The canonical PINK1Parkin-mediated mitophagy enables the recognition and ubiquitination of damaged mitochondria, facilitating their autophagic clearance, while the receptor-mediated pathways involving BNIP3, NIX, and FUNDC1 provide additional layers of regulation, particularly under stress conditions relevant to aging and NDDs [59,60,61,62]