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Most patients notice appetite regulation within a few weeks, with visible weight loss typically starting around one to two months into treatment

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El desarrollo de la artritis reumatoide se basa en una predisposicin gentica, como los alelos HLA-DR4, que crean anticuerpos contra las protenas citrulinadas, y en factores desencadenantes ambientales, como las infecciones o el tabaquismo [8]