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Trx is a widely distributed small dithiol protein that contains 104 amino acids, including one disulfide bridge, two SH groups, and a conserved active site (Trp-Cys-Gly-Pro-Cys) [119]

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reported that SFN exerted its neuroprotective effect in several ways, such as mTOR-dependent prevention of neuronal apoptosis, Nrf2-dependent reductions in oxidative stress, and restoration of normal autophagy [17]