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Overoxidation of the selenoprotein would inactivate that protein, and thus prevent it from carrying out its oxidative functions

Thomas MK, Nikooienejad A, Bray R, Cui X, Wilson J, Duffin K, Milicevic Z, Haupt A, Robins DA

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Many approaches have been attempted in order to alleviate or prevent liver disease via the reduction of oxidative stress (Li et al