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Additional platforms exploit GSH-mediated cleavage of disulfide or polysulfide bonds to induce ferroptosis and pyroptosis

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CAS 2381089-83-2 MW 4731.33 Da Sequence Not listed Half-life Discussed in research notes Formula C221H342N46O68 Purity 99.49% Form Lyophilized powder Class GIP/GLP-1/Glucagon Triple Receptor Agonist The dossier

The schistosomicidal activities of PZQ and of potassium antimonial tartrate, a drug used in the past for schistosomiasis and a TGR inhibitor, are reduced in immunosuppressed mice 65 , indicating a crucial role of the host immune system in the mechanism of action of schistosomicidal agents in vivo