(This is associative evidence and may reflect confounding by indication, surveillance patterns, and glycaemic differences.) For post-marketing pharmacovigilance, FAERS-based analyses of semaglutide identify multiple safety signals (e.g., gastrointestinal obstruction-related terms, dehydration/volume depletion in some GLP-1RA analyses), but vulvovaginal dryness/infection/discharge/pain are not prominent as labelled risks in the major semaglutide FAERS disproportionality paper retrieved here
Mounjaro and Zepbound are single-dose pens
The level of typical biomarker of oxidative stress 8-hydroxy-2-deoxyguanosine is higher in uterine myomas than in control tissues and correlates with the size of the tumor
A placebo capsule, containing excipients but no peptide, was also administered in the same way, and peptide administered as a free solution by injection was also tested
Early identification and management of adverse effects or changes in symptoms associated with oral antidiabetic agents are essential to prevent complications and optimize treatment outcomes
