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placebo from baseline to 13 weeks, but there were no differences between the study drug and placebo groups for other cardiometabolic markers

Singh R (2010) Autophagy and regulation of lipid metabolism

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Have realistic expectations about supplement outcomes: If you understand that botanical supplements typically produce more modest and gradual effects compared to pharmaceutical interventions, and you view Patchie as one component of a broader wellness approach rather than a standalone solution, your expectations are appropriately calibrated

2 Less common but significantly more severe side effects have been documented, including gastroparesis, pancreatitis, kidney complications, the development of arthritis, vision loss and possibly even thyroid cancer