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GLP-1R can also suppress cardiac hypertrophy induced by Ang II through attenuating the Nox4-histone deacetylase 4 (HDAC4) axis [162]

To investigate the direct effect of GLP-1 on sperm, we conducted interventions with liraglutide and semaglutide in sperm suspensions collected from cauda epididymis and in four testicular cell lines (including spermatogonia, spermatocytes, Leydig cells and Sertoli cells)

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