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Obesity Reviews (2018) : A meta-analysis of multiple studies showed that 500 mg to 2,000 mg of L-Carnitine can promote fat loss, and there was no significant difference in results between 1,000 mg and 2,000 mg doses

Ryter and Choi, 2015

The mechanism behind this hyperpigmentation involves the increased production of melanocyte-stimulating hormone (MSH) and other pro-opiomelanocortin byproducts