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In a 24-week randomized human trial, participants receiving semaglutide experienced: Reduced joint pain Improved mobility MRI-observed cartilage thickening in weight-bearing areas Considering that osteoarthritis affects roughly 600 million people worldwide and remains a leading cause of disability, these findings could point toward a future where treatments target the underlying biology of joint degeneration, not just the symptoms

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Depending on where you are in the country, that can even be done at home, but in some places, that needs to happen in the hospital, Guttman says