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The Bottom Line GLP-1 receptor agonist medications are changing lives for many people, but they also change the way the digestive system works and, for many users, reduce the dietary fiber and nutrient diversity that a healthy gut microbiome depends on

Especially for people using GLP-1 medications, these internal changes can happen before noticeable changes on the scale

You inject, the fatigue hits while you are sleeping, and you wake up feeling relatively normal

Whether that cost difference justifies the trade-offs - including the lack of FDA review of the finished compounded product - is a question each individual should discuss with their healthcare provider

Laufer, P