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A number of agents have been shown to reduce lipofuscin accumulation, including anti-helminthic flubendazole [65] and zinc [66] in human retinal pigment epithelium, rapamycin in animal cardiomyocytes [67] and murine hepatocytes [68]

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Research shows GLP-1 therapy reduces appetite by 30 to 40% in postmenopausal women, independent of age-related metabolic changes